Based on the available data, a high milk docosahexaenoic acid supply to very low-birth-weight infants and to extremely low-birth-weight infants at levels that support tissue accretion rates similar to the high rates of intrauterine deposition has the potential to enhance the early visual and cognitive development, and to reduce the occurrence of adverse events, such as severe developmental delay, bronchopulmonary dysplasia, necrotizing enterocolitis, and allergic manifestations in infancy and early childhood. Possibly subgroups of preterm infants achieve greater benefits as well as infants with genotypes predicting a low rate of endogenous long-chain polyunsaturated fatty acids formation.

PMID: 28159211

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