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                |  2005/07/01 | 
               
               
                | OstInt - Vitamin D To Lower Risk Of Fracture   | 
               
               
                
                    Dawson-Hughes B, Heaney RP, Holick MF, et al.  Estimates of optimal vitamin D status. Osteoporos Int, 2005;16(7):713-716.  
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                Vitamin D has captured attention as an important determinant of bone health, but there is no common definition of optimal vitamin D status.  
 
Herein, we address the question: What is the optimal circulating level of 25-hydroxyvitamin D [25(OH)D] for the skeleton? The opinions of the authors on the minimum level of serum 25(OH)D that is optimal for fracture prevention varied between 50 and 80 nmol/l. However, for five of the six authors, the minimum desirable 25(OH)D concentration clusters between 70 and 80 nmol/l.  
 
The authors recognize that the average older man and woman will need intakes of at least 20 to 25 mcg (800 to 1,000 IU) per day of vitamin D(3 ) to reach a serum 25(OH)D level of 75 nmol/l.  
 
Based on the available evidence, we believe that if older men and women maintain serum levels of 25(OH)D that are higher than the consensus median threshold of 75 nmol/l, they will be at lower risk of fracture. 
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                | Source: 
								http://www.ncbi.nlm.nih.gov/pubmed/15776217
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